PEEP Strategies and Mechanical Power in Robotic Surgery

Starting soon · Not applicable

Conditions studied: Postoperative Pulmonary Complications, Impaired Oxygenation, Mechanical Ventilation

In brief

Robotic surgery requires pneumoperitoneum and steep Trendelenburg positioning, which significantly impair respiratory mechanics and increase the risk of postoperative pulmonary complications. Positive end-expiratory pressure (PEEP) is a key determinant of lung recruitment; however, fixed PEEP strategies may not be optimal for all patients. Individualized PEEP titration strategies, including incremental and decremental approaches, may better optimize lung mechanics. This randomized controlled trial aims to compare the effects of incremental, decremental, and fixed PEEP strategies on cumulative mechanical power (MP-AUC) and postoperative oxygenation in patients undergoing robotic surgery.

Key facts

Study ID

NCT07536464

Run by

Ankara City Hospital Bilkent

People needed

120

Starts

2026-04-15

Expected to finish

2026-06-30

Last updated by the study team

2026-04-17

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age>= 18
• ASA I-III
• Elective robotic surgery

You may not qualify if…

• COPD GOLD ≥2
• Restrictive lung disease
• BMI >40 kg/m²
• Heart failure
• Preoperative oxygen requirement
• Need for postoperative mechanical ventilation
• Refusal to participate

Full record on ClinicalTrials.gov

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