Gas6 and Soluble MerTK in Periodontal Diseases
Recruiting now
Conditions studied: Periodontitis
In brief
This study aimed to investigate gingival crevicular fluid (GCF) and serum soluble MerTK (sMerTK) and Gas6 levels in periodontal health and disease. A total of 90 individuals, 30 patients with stage III grade B periodontitis, 30 with gingivitis and 30 periodontally healthy individuals were included. Whole-mouth and site-specific clinical periodontal parameters including probing depth, clinical attachment level, bleeding on probing, gingival index, plaque index were recorded. GCF and serum sMerTK and Gas6 levels were measured by enzyme-linked immunosorbent assay. Statistical analysis was performed by using non-parametric tests.
Key facts
- Study ID
- NCT07535177
- Run by
- Abant Izzet Baysal University
- People needed
- 90
- Starts
- 2026-03-25
- Expected to finish
- 2026-05-20
- Last updated by the study team
- 2026-04-16
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Individuals without systemic diseases that may affect periodontal tissues (such as cardiovascular diseases, atherosclerosis, immune system disorders, rheumatoid arthritis, obesity, cancer, and diabetes)
- Individuals who have not used antibiotics within the last 3 months
- Individuals not taking any medications known to affect periodontal tissues
- Individuals without infectious diseases such as HIV, hepatitis B virus (HBV), or tuberculosis
- Individuals with at least 16 natural teeth, excluding third molars
- Individuals aged 18 years and older
You may not qualify if…
- Pregnant or lactating individuals
- Individuals who have received periodontal treatment within the last 6 months
- Current smokers
Where it is running
- Bolu Abant Izzet Baysal University Faculty of Dentistry — Bolu, Bolu, Turkey (Türkiye) (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.