Pontic Site Development With or Without Fixed Partial Denture
Recruiting now · Not applicable
Conditions studied: Mucogingival Defects, Pontic Site Development, Keratinized Tissue Deficiency, Connective Tissue Graft
In brief
This study aims to evaluate the effectiveness of soft tissue augmentation using connective tissue graft (CTG) in pontic site defects. It compares clinical and volumetric outcomes between sites with an existing fixed partial denture (FDP) and sites without an FDP. Following tooth extraction, alveolar ridge resorption often leads to soft tissue defects that can compromise esthetics, function, and prosthetic outcomes. CTG is considered the gold standard for soft tissue augmentation due to its predictable improvement in tissue thickness and stability. In this non-randomized clinical trial, patients with single edentulous sites in the esthetic zone will undergo CTG using a standardized surgical technique. The primary outcome is keratinized tissue thickness, while secondary outcomes include keratinized tissue width, volumetric soft tissue changes, esthetic evaluation (Pink Esthetic Score), plaque index, post-operative pain, and patient satisfaction. Clinical and digital assessments will be conducted preoperatively and at follow-up intervals up to 6 months. The study aims to determine whether performing CTG around an existing bridge provides comparable or improved outcomes compared to sites without a bridge, potentially offering a less invasive alternative to prosthetic replacement.
Key facts
- Study ID
- NCT07535060
- Run by
- Cairo University
- People needed
- 20
- Starts
- 2025-10-06
- Expected to finish
- 2027-06-01
- Last updated by the study team
- 2026-05-01
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Patients will on missing tooth in the esthetic zone (2nd premolar to 2nd premolar), missing at least 3 months prior to recruitment, with or without FPD
- Systemically free patient
- ≥18 years of age
- Intact gingival tissue with at least 2mm keratinized tissue in adjacent teeth
- Patients accept to provide informed consent
You may not qualify if…
- Smokers.
- Pregnancy and lactation
- Periodontitis
- Severe gagging reflex
- Handicapped and mentally challenged patients
- Active soft tissue infection
Where it is running
- Faculty of Dentistry, Cairo University — Cairo, Egypt (enrolling)
Full record on ClinicalTrials.gov
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