Mechanical Power Ventilation in RALP

Starting soon · Not applicable

Conditions studied: Postoperative Pulmonary Dysfunction, Oxygenation Impairment, Robot-Assisted Radical Prostatectomy

In brief

Robot-assisted laparoscopic radical prostatectomy (RALP) requires steep Trendelenburg positioning and pneumoperitoneum, which adversely affect respiratory mechanics and may lead to impaired postoperative oxygenation. Mechanical power (MP) has recently emerged as a comprehensive parameter reflecting the total energy delivered from the ventilator to the respiratory system and may be associated with ventilator-induced lung injury. This prospective randomized controlled trial aims to evaluate whether a mechanical power-targeted ventilation strategy improves postoperative oxygenation compared to standard ventilation in patients undergoing RALP. The primary outcome is the oxygenation index (OSI) at the postoperative second hour. Secondary outcomes include PaO₂/FiO₂ ratio, postoperative pulmonary complications, and length of hospital stay.

Key facts

Study ID

NCT07534553

Run by

Ankara City Hospital Bilkent

People needed

80

Starts

2026-04-15

Expected to finish

2026-07-30

Last updated by the study team

2026-04-16

Who can join

Age: 18 and older. Sex: male. Healthy volunteers: accepted.

You may qualify if…

• Age ≥18 years
• Elective RALP
• ASA I-III

You may not qualify if…

• Severe pulmonary disease (advanced COPD, ILD)
• Preoperative oxygen requirement
• Emergency surgery
• BMI > 40 kg/m²

Where it is running

• Ankara Bilkent City Hospital — Ankara, Turkey (Türkiye)

Full record on ClinicalTrials.gov

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