Piloting a Generative Artificial Intelligence Chatbot in a Mobile Weight Loss Program
Running, not enrolling · Not applicable
Conditions studied: Overweight and/or Obesity
In brief
The goal of this study is to learn if integrating a chatbot into an existing 12-week smartphone-delivered behavioral weight loss program is feasible and effective for weight loss among young adults. Researchers will compare a standard behavioral weight loss program for young adults that delivers 1-2 brief messages per day (AGILE) to the same program with a chatbot that offers additional behavior change support integrated into the app (AGILE + Chatbot) to determine if the program with the chatbot is feasible, acceptable to participants, and improves program engagement and weight change compared to AGILE alone.
Key facts
- Study ID
- NCT07534254
- Run by
- University of North Carolina, Chapel Hill
- People needed
- 20
- Starts
- 2026-03-23
- Expected to finish
- 2026-09-28
- Last updated by the study team
- 2026-06-26
Who can join
Age: 18 and older, up to 39. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- body mass index (BMI) of 25-45 kg/m\^2
- English-speaking and writing
- own an iPhone with a data plan
- willing to be randomized to either treatment group
You may not qualify if…
- Type 1 diabetes or currently receiving medical treatment for Type 2 diabetes
- Other health problems which may influence the ability to walk for physical activity or be associated with unintentional weight change, including tuberculosis, currently receiving cancer treatment, or history of a heart attack or stroke
- Report a heart condition, chest pain during periods of activity or rest, or loss of consciousness on the Physical Activity Readiness Questionnaire (PAR-Q; items 1-4), or report any other reason not able to walk for physical activity
- Lost 10 or more pounds (and kept it off) in the last 6 months
- Currently taking weight loss medications
- History of weight loss surgery or planning weight loss surgery in the next 4 months
- Report a past diagnosis of, or receiving treatment for, a DSM-5-TR (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision) eating disorder (anorexia nervosa or bulimia nervosa)
- Currently pregnant or planning to become pregnant within the next 4 months
- Health or psychological diagnoses that preclude participation in a prescribed dietary and exercise program, including history of or diagnosis of schizophrenia or bipolar disorder, hospitalization for a psychiatric diagnosis in the past year, current diagnosis of alcohol or substance abuse
- Another member of the household is a participant or staff member on this trial
- Currently participating in a weight loss, nutrition, or physical activity study or program or other study that would interfere with this study
- Not willing to wear a Fitbit every day
- Have participated in another study conducted by the UNC Weight Research Program within the past 12 months
Where it is running
- University of North Carolina at Chapel Hill — Chapel Hill, North Carolina, United States
Full record on ClinicalTrials.gov
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