Erector Spinae Plane Block Versus External Oblique Intercostal Plane Block for Analgesia in Open Cholecystectomy

Starting soon · Not applicable

Conditions studied: Cholecystectomy, Postoperative Pain, Erector Spinae Plane Block, Regional Anesthesia

In brief

This randomized controlled trial aims to compare the analgesic efficacy of bilateral ultrasound-guided erector spinae plane block (ESPB) versus bilateral external oblique intercostal plane (EOI) block in patients undergoing open cholecystectomy. Patients will be randomly allocated into two groups to receive either ESPB or EOI block in addition to standard general anesthesia. The primary outcome is postoperative pain score assessed using the Numerical Rating Scale (NRS) at 2 hours after surgery. Secondary outcomes include intraoperative opioid consumption, postoperative nalbuphine requirements, time to first analgesic request, and hemodynamic changes. This study seeks to determine the more effective regional anesthesia technique for improving perioperative analgesia in open cholecystectomy.

Key facts

Study ID

NCT07533279

Run by

Sohag University

People needed

66

Starts

2026-06-01

Expected to finish

2027-05-01

Last updated by the study team

2026-04-16

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult patients aged 18-65 years.
• Patients scheduled for elective open cholecystectomy.
• American Society of Anesthesiologists (ASA) physical status I-II.
• Patients who provide informed consent.

You may not qualify if…

• Patient refusal.
• Known allergy to local anesthetics.
• Coagulopathy or anticoagulant therapy.
• Infection at the site of injection.
• Severe hepatic, renal, or cardiac disease.
• Body mass index (BMI) > 35 kg/m².
• Pregnancy.

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.