Diode Laser-Assisted Periodontal Therapy in Kidney Transplant Recipients
Recruiting now · Not applicable
Conditions studied: Periodontitis, Kidney Transplant Recipients
In brief
This randomized controlled trial evaluates the efficacy of diode laser-assisted non-surgical periodontal therapy in kidney transplant recipients with periodontitis. Eighty participants will be allocated to two parallel groups: scaling and root planing (SRP) with adjunctive diode laser therapy or SRP alone. Clinical periodontal parameters, blood biomarkers, radiographic findings, and subgingival microbiome profiles will be assessed at baseline and during follow-up. The study aims to determine whether adjunctive diode laser therapy provides superior clinical and biological improvement compared with SRP alone.
Key facts
- Study ID
- NCT07532694
- Run by
- Military Hospital 103
- People needed
- 80
- Starts
- 2025-12-09
- Expected to finish
- 2026-06-09
- Last updated by the study team
- 2026-04-16
Who can join
Age: any. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Kidney transplant recipients aged 18 years or older.
- Diagnosis of periodontitis according to the study case definition.
- Medically stable and able to undergo non-surgical periodontal treatment.
- Willing and able to provide written informed consent and attend follow-up visits.
You may not qualify if…
- - Periodontal treatment or systemic antibiotic use within the predefined exclusion window in the protocol.
- Acute oral infection requiring urgent treatment.
- Pregnancy or lactation, if excluded by the approved protocol.
- Serious systemic condition or clinical instability judged by investigators to preclude study participation.
- Inability to comply with study procedures or follow-up schedule.
Where it is running
- 103 Military Hospital — Hanoi, Hadong, Vietnam (enrolling)
- Vietnam Military Medical University — Hanoi, QUẬN HÀ ĐÔNG, Vietnam (enrolling)
Full record on ClinicalTrials.gov
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