Comparative Effect of Pursed Lip Breathing Alone and Combined With Alternate Nostril Breathing on Pulmonary Function Test and Quality of Life in Patients in Grade I COPD Patients.

Recruiting now · Not applicable

Conditions studied: COPD Grade I

In brief

Chronic Obstructive Pulmonary Disease (COPD) is a progressive respiratory disorder characterized by airflow limitation, breathlessness, and reduced quality of life. Breathing exercises are commonly used in pulmonary rehabilitation to improve respiratory efficiency and functional capacity. Among these techniques, pursed lip breathing (PLB) helps slow expiration, reduce air trapping, and improve ventilation, while alternate nostril breathing (ANB), a yogic breathing technique, may enhance respiratory control and relaxation. The purpose of this study is to determine the effects of pursed lip breathing alone compared with the combined effect of pursed lip breathing and alternate nostril breathing on pulmonary function and quality of life in patients with Grade I COPD. This randomized controlled trial will include approximately 40 participants diagnosed with mild COPD. The participants will be divided into two groups: one group will perform pursed lip breathing exercises, while the other group will perform a combination of pursed lip breathing and alternate nostril breathing. Pulmonary function tests and quality of life assessments will be used as outcome measures to evaluate the effectiveness of these interventions. The study aims to determine whether combining both breathing techniques provides greater improvement in respiratory function and patient well being than pursed lip breathing alone. The findings may contribute to developing more effective physiotherapy based pulmonary rehabilitation strategies for patients with COPD.

Key facts

Study ID

NCT07531771

Run by

Foundation University Islamabad

People needed

40

Starts

2026-02-28

Expected to finish

2026-05-15

Last updated by the study team

2026-04-15

Who can join

Age: 40 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients diagnosed with Grade I COPD (FEV₁ > 80% predicted)
• Age between 40 to 65 years.
• Both male and female patients.
• Patients able to follow verbal instructions and perform breathing exercises.
• Patients willing to provide written informed consent.

You may not qualify if…

• History of orthopedic conditions limiting sitting or breathing exercises.
• Recent respiratory infections or COPD exacerbations within the past 4 weeks.
• Neurological or cognitive impairments.
• Recent thoracic or abdominal surgeries.
• Regular practitioners of yoga or alternate nostril breathing.

Where it is running

• Foundation University Islamabad — Islamabad, Pakistan (enrolling)

Full record on ClinicalTrials.gov

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