Assessment of Intra-abdominal Pressure During the Perioperative Period of Hernia Repair

Recruiting now · Not applicable

Conditions studied: Hernia Incisional

In brief

Thousands of patients worldwide undergo abdominal surgery every day; 2-11% of laparotomies will progress to an incisional hernia, particularly midline laparotomies, which are associated with higher hernia rates, reaching up to 70% in obese patients (1,2). Long-term recurrence after incisional hernia repair is close to 30% after primary repair and may increase to 70% in cases of iterative (redo) surgery (3). The main risk factors for incisional hernia formation or recurrence include surgical site infection, surgical technique, respiratory insufficiency (COPD), as well as overweight and obesity, the prevalence of which is rapidly increasing. Midline incisional hernias are the most frequent and represent a significant public health issue. In abdominal wall surgery, some teams perform so-called tension-free repairs, whereas others favor repairs under tension. The tension-free concept may be associated with a lower recurrence rate. However, this intuitive concept has never been mechanically defined, using perioperative pressure measurements or surface tension assessment. Few studies have investigated abdominal pressure and muscle tension measurements in relation to abdominal wall surgery. The aim of this study is to evaluate a protocol for measuring abdominal pressures during open repair of midline incisional hernia.

Key facts

Study ID

NCT07531615

Run by

Centre Hospitalier Universitaire de Nice

People needed

10

Starts

2026-07-30

Expected to finish

2028-08-01

Last updated by the study team

2026-07-02

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Midline incisional hernias with a hernia defect width between 4 and 10 cm in the transverse axis, corresponding to W2 according to the EHS classification
• M2, M3, and M4 locations according to the EHS classification (i.e., hernia defects located from 3 cm below the xiphoid process to 3 cm above the upper border of the pubic symphysis)
• Patients scheduled for elective open midline incisional hernia repair with retromuscular mesh placement
• Provision of written informed consent
• Affiliation with a national health insurance system

You may not qualify if…

• Other types of incisional hernia
• Minimally invasive surgery (laparoscopic or robotic approach)
• Patients under legal protection (guardianship or curatorship), or patients unable to participate in a clinical study in accordance with Article L.1121-16 of the French Public Health Code
• Pregnant or breastfeeding women of childbearing age

Where it is running

• CHU de Nice — Nice, Alpes-Maritimes, France (enrolling)

Full record on ClinicalTrials.gov

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