Statins Study in Children of Acute Kawasaki Disease With Coronary Artery Abnormalities

Recruiting now · Phase 3

Conditions studied: Kawasaki Disease, Coronary Artery Abnormalities

In brief

The goal of this observational study is to learn about the safety and effects of atorvastatin in treatment of Chinese Kawasaki disease (KD) children complicated with coronary artery abnormalities (CAA) in acute phase. The main questions it aims to answer are: Is atorvastatin safe in Chinese children of acute KD? Does atorvastatin contribute to control the acute inflammation in KD and improve the CAA?

Key facts

Study ID

NCT07530640

Run by

Children's Hospital of Fudan University

People needed

9

Starts

2026-06-08

Expected to finish

2027-09-30

Last updated by the study team

2026-06-16

Who can join

Age: 2 and older, up to 18. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• KD complicated with CAA, less than 20 days after the onset of KD, or more than 20 days after onset but the KD inflammation has not been controled.
• IVIG and/or other anti-inflammatory treatments have been used/are being used.
• The guardians agree to atorvastatin treatment and sign the informed consent form.

You may not qualify if…

• Patients with history of family hypercholesterolemia/taking statins/severe chronic diseases.
• Patients with abnormal laboratory data including CK≥500U/L, total cholesterol<3.1mmol/L, ALT or AST≥ 2 times the upper limit of normal.
• The guardians do not agree to atorvastatin treatment.

Where it is running

• Children's Hospital of Fudan University — Shanghai, China (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.