A Longitudinal Cohort Study on the Changes of Physiological Mechanisms in Children After Biliary Tract Reconstruction
Recruiting now
Conditions studied: Choledochal Cyst
In brief
Through observational studies, the long-term changes in liver function, metabolic state, immune response and other aspects of children after biliary tract reconstruction during their growth process were systematically explored. The risks of these long-term physiological changes on chronic diseases such as cardiovascular diseases, diabetic diseases and liver cirrhosis in adulthood, as well as their impacts on cognitive function, musculoskeletal health and other aspects were evaluated. How do early physiological changes affect a patient's long-term health? Are there any potential biomarkers that can predict future health outcomes? Based on the research results, preventive and intervention measures that are helpful in reducing the risk of long-term complications are proposed.
Key facts
- Study ID
- NCT07530354
- Run by
- Wuhan Children's Hospital
- People needed
- 100
- Starts
- 2025-05-01
- Expected to finish
- 2035-04-30
- Last updated by the study team
- 2026-04-15
Who can join
Age: any, up to 16. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Healthy children matched by age and gender were selected as the control group
You may not qualify if…
- Combined with other serious diseases (such as cancer, autoimmune diseases), having obvious liver function abnormalities before surgery or being undergoing other major treatments.
Where it is running
- Wuhan Children's Hospital — Wuhan, Hubei, China (enrolling)
- Wuhan Children'S Hospital — Wuhan, Hubei, China (enrolling)
- Wuhan Children'S Hospital — Wuhan, Hubei, China (enrolling)
Full record on ClinicalTrials.gov
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