Functional and Respiratory Predictors of Early Postoperative Outcomes

Recruiting now

Conditions studied: Colorectal Cancer, Functional Status, Respiratory Parameters, Clinical Outcomes

In brief

Functional status is a fundamental indicator reflecting a patient's ability to perform activities of daily living and is closely associated with early postoperative outcomes. Patients with low functional capacity are known to have an increased risk of postoperative complications, prolonged length of hospital stay, and higher mortality rates. Similarly, respiratory function plays a decisive role in the development of postoperative complications and influences early surgical outcomes. In the preoperative period, inadequate respiratory capacity and poor functional performance increase the risk of postoperative pulmonary complications and delayed recovery. Therefore, functional and respiratory assessments are regarded as integral components of the preoperative preparation process. Early outcomes in patients undergoing colorectal cancer surgery are of critical importance in reducing mortality and morbidity. In this surgical population, advanced age, comorbidities, and diminished physical capacity may further increase the risk of postoperative complications. Accordingly, the evaluation of preoperative functional status and physiological reserve has gained increasing importance for risk stratification and perioperative management. However, studies examining the impact of functional status and respiratory parameters on early surgical outcomes in patients with colorectal cancer remain limited. Consequently, the available evidence is insufficient to establish a standardized assessment approach in clinical practice. Moreover, objective evaluation of patients' functional and respiratory capacities in the preoperative period is essential for predicting surgical risk and planning individualized perioperative care. Determining the relationships between these parameters and early clinical outcomes may facilitate the identification of high-risk patients and contribute to the development of targeted strategies aimed at preventing postoperative complications. Findings obtained in this context are expected to provide a scientific basis for clinical decision-making and multidisciplinary patient management in individuals undergoing colorectal cancer surgery, thereby guiding clinical practice.

Key facts

Study ID

NCT07529301

Run by

Müşerref Ebru YALÇIN

People needed

42

Starts

2026-03-01

Expected to finish

2027-02-25

Last updated by the study team

2026-04-14

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Being between 18 and 80 years of age
• Voluntary agreement to participate in the study

You may not qualify if…

• Withdrawal from the study at the participant's own request
• Elimination Criteria
• Presence of a musculoskeletal condition that may prevent completion of the planned assessments
• Presence of a mental impairment
• History of psychiatric disorder
• History of previous major surgery

Where it is running

• İnönü University Turgut Özal Medical Center General Surgery Polyclinic — Malatya, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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