Impact of Theta Burst Repetitive Transcranial Magnetic Stimulation on the Patient's Self-reported Improvement in Their Motor Functional Neurological Disorder
Recruiting now
Conditions studied: Functional Neurological Disorder, Motor FND
In brief
Functional neurological disorder (FND) is a condition that causes significant suffering and disability. It is defined by the presence of neurological symptoms that interfere with an individual's functioning and are not consistent with any known anatomical lesion but that causes significant functional impairment. The investigators are particularly interested in motor symptoms (abnormal movements or motor deficits). Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive and acceptable treatment that has proven effective in certain chronic pain conditions, depression, and OCD. The investigators would like to evaluate the impact of rTMS on the patient's overall perception of change, particularly on the clinical symptoms of motor FND. Secondary objectives include evaluating the overall effect on symptoms from the clinician's perspective, the effect on quality of life, on depressive and anxiety symptoms and associated dissociation, as well as evaluating any changes in the sense of agency and identifying the side effects of rTMS treatment.
Key facts
- Study ID
- NCT07527403
- Run by
- Hospital Center Guillaume Régnier
- People needed
- 22
- Starts
- 2026-03-13
- Expected to finish
- 2028-03-01
- Last updated by the study team
- 2026-04-20
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients over 18
- Patients with FND, either deficits or abnormal movements, diagnosed by a neurologist.
- Patients with an indication for validated neuronavigated rTMS treatment.
- Patients who have indicated that they do not object to participating in the study.
You may not qualify if…
- Patients subject to legal protection (legal guardianship, conservatorship, trusteeship)
- Patients deprived of liberty
Where it is running
- Centre Hospitalier Guillaume Régnier — Rennes, France (enrolling)
Full record on ClinicalTrials.gov
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