Effects of Glycemic Control and Clinical Parameters on Tibial Nerve Conduction Latency in Diabetic Peripheral Neuropathy

Enrolling by invitation

Conditions studied: Diabetic Peripheral Neuropathy, Diabetes Mellitus

In brief

This observational cross-sectional study aims to investigate the effects of glycemic control and clinical parameters on tibial nerve conduction latency in individuals with diabetic peripheral neuropathy. Adults aged 45 to 76 years with diabetic peripheral neuropathy will be evaluated at a neurology and clinical neurophysiology clinic. Data collection will include demographic and clinical characteristics, diabetes type and duration, fasting blood glucose, and HbA1c values obtained from routine clinical records. Participants will also be assessed using the Michigan Neuropathy Screening Instrument (MNSI), including both the questionnaire and physical examination components. Nerve conduction studies will be performed using standard electromyography procedures, and tibial nerve conduction latency will be recorded. The study will examine the relationship between tibial nerve conduction latency and glycemic control parameters, neuropathy screening scores, and diabetes duration. The findings may help improve early identification and clinical evaluation of diabetic peripheral neuropathy.

Key facts

Study ID

NCT07525882

Run by

Fenerbahce University

People needed

50

Starts

2026-04-13

Expected to finish

2026-06-01

Last updated by the study team

2026-04-23

Who can join

Age: 45 and older, up to 76. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Participants aged 45 to 76 years
• Diagnosis of diabetes-related neuropathy based on laboratory tests, clinical findings, and nerve conduction test (NCT) results

You may not qualify if…

• History of autoimmune disease, cerebrovascular disease, or chronic infectious disease
• Diagnosis of cancer or a history of chemotherapy and/or radiotherapy
• Radicular neuropathy
• Chronic kidney failure or liver failure
• Alcoholism or other substance dependence
• Mental or physical disability (including blindness)
• Inability to speak Turkish

Where it is running

• Fenerbahçe University — Istanbul, Ataşehir, Turkey (Türkiye)

Full record on ClinicalTrials.gov

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