Pain & Reward Neuromodulation of CNS Circuits

Enrolling by invitation · Not applicable

Conditions studied: Fibromyalgia Syndrome, Fibromyalgia, Chronic Pain and Fatigue

In brief

This pilot feasibility study aims to evaluate transcranial magnetic stimulation (TMS) targeting the prefrontal cortex in patients with fibromyalgia syndrome (FMS). The study will assess preliminary efficacy and mechanisms of central nervous system changes using neuroimaging, behavioral tasks, sensory testing, and neuroimmune markers. Participants will undergo MRI scans, multi-day TMS sessions, and complete questionnaires. The goal is to generate pilot data for future trials on neuromodulation for chronic pain.

Key facts

Study ID
NCT07525063
Run by
Duke University
People needed
30
Starts
2026-07-21
Expected to finish
2027-06-01
Last updated by the study team
2026-07-28

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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