Femoral Triangle Block vs Adductor Canal Block on Early Quadriceps Function After Total Knee Arthroplasty

Recruiting now · Not applicable

Conditions studied: Total Knee Arthroplasty, Total Knee Arthroplasty Recovery, Total Knee Arthroplasty Postoperative Pain

In brief

The goal of this clinical trial is to compare the effects of femoral triangle block (FTB) and adductor canal block (ACB) on early quadriceps function after total knee arthroplasty (TKA). The main question it aims to answer is whether FTB causes more early quadriceps functional impairment than ACB under a standardized multimodal analgesia protocol. Researchers will compare FTB and ACB using a composite binary functional outcome measured 6 hours after block completion. Quadriceps functional impairment is defined as the inability to perform a structured straight leg raise or quadriceps muscle strength \<50% of the preoperative baseline. Participants will be randomly assigned to receive ultrasound-guided FTB or ACB. All participants will also receive a popliteal plexus block and standardized multimodal analgesia.

Key facts

Study ID

NCT07524387

Run by

Social Medical Corporation Daiyukai

People needed

136

Starts

2026-04-13

Expected to finish

2029-03-31

Last updated by the study team

2026-04-16

Who can join

Age: 20 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult patients (≥ 20 years of age) are scheduled to undergo primary unilateral TKA.
• American Society of Anesthesiologists (ASA) physical status I-III.
• Ability to ambulate independently prior to surgery.
• Ability to understand the study procedures and provide written informed consent.
• Planned perioperative anesthesia management including regional anesthesia as part of standard clinical care.
• Ability to extend the knee below 30 degrees preoperatively (no knee extension contracture)

You may not qualify if…

• Known allergy or contraindication to local anesthetic agents used in this study.
• Pre-existing neurological or neuromuscular disorders affect lower limb strength or motor control.
• Severe cognitive impairment or psychiatric conditions interfere with study participation or assessment.
• History of revision knee arthroplasty on the operative side.
• Severe preoperative quadriceps weakness that precludes reliable baseline strength assessment.
• Any condition deemed by the investigator to make participation inappropriate.

Where it is running

• Department of Anesthesiology, Daiyukai General Hospital — Ichinomiya, Aichi-ken, Japan (enrolling)

Full record on ClinicalTrials.gov

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