Effect of Extracorporeal Shock Wave Therapy on Spasticity and Mobility in Stroke Patients

Starting soon · Not applicable · Has a placebo group

Conditions studied: Stroke, Post-Stroke Spasticity, Lower Limb Spasticity

In brief

This study aims to evaluate the effectiveness of extracorporeal shock wave therapy (ESWT) in individuals with lower limb spasticity following stroke. Spasticity is a common complication after stroke and can negatively affect walking ability, mobility, and quality of life. Participants will be randomly assigned to one of two groups. Both groups will receive a standard physiotherapy and rehabilitation program. In addition, the intervention group will receive ESWT applied to the lower limb muscles, while the control group will receive a sham (placebo) ESWT application. The treatment program will be conducted three times per week for four weeks. Clinical assessments will be performed at baseline, after treatment, and during follow-up. The main outcomes of the study include muscle tone (spasticity), walking performance, motor function, and quality of life. The results of this study may help improve rehabilitation strategies and provide evidence for the use of ESWT in stroke patients.

Key facts

Study ID

NCT07523243

Run by

Istanbul Medipol University Hospital

People needed

85

Starts

2026-04-01

Expected to finish

2026-06-20

Last updated by the study team

2026-04-14

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults aged 18-65 years
• Diagnosed with ischemic or hemorrhagic stroke at least 3 months prior to enrollment Presence of lower extremity spasticity with a Modified Ashworth Scale (MAS) score ≥1+
• Ability to walk independently with or without assistive devices
• Ability to understand and follow instructions for exercise interventions and assessments
• Provided written informed consent

You may not qualify if…

• Receipt of botulinum toxin injection in the affected lower limb within the last 3 months
• Severe cognitive impairment preventing participation in assessments
• Presence of fixed joint contractures limiting range of motion
• Orthopedic or musculoskeletal disorders affecting lower limb function (e.g., fracture, severe osteoarthritis)
• Uncontrolled cardiovascular, respiratory, or systemic disease contraindicating exercise
• Participation in another interventional clinical trial
• Any condition judged by the investigator to interfere with participation or safety

Full record on ClinicalTrials.gov

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