Intrathecal Dexmedetomidine With Bupivacaine, in Patients Undergoing Knee Orthopedic Surgery

Recruiting now · Not applicable

Conditions studied: Intrathecal Dexmedetomidine, Bupivacaine, Knee Orthopedic Surgery

In brief

This study aims to compare the duration of analgesia (as the primary outcome) and adverse effects (as the secondary outcome) after intrathecal administration of dexmedetomidine with hyperbaric bupivacaine to patients undergoing knee orthopedic surgery.

Key facts

Study ID

NCT07522736

Run by

Cairo University

People needed

120

Starts

2025-03-01

Expected to finish

2026-08-30

Last updated by the study team

2026-04-13

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age from 18 to 65 years.
• American Society of Anesthesiologists (ASA) physical status I-II.
• Male patients scheduled for knee orthopedic surgery.

You may not qualify if…

• Patients with psychiatric disorders.
• History of drug addiction.
• Contraindication for regional anesthesia.
• History of hypersensitivity to the study drugs.
• Previous administration of opioids and/or other central nervous system depressants during current hospital admission.

Where it is running

• Cairo University — Cairo, Egypt (enrolling)

Full record on ClinicalTrials.gov

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