Fluid-responsiveness Assessment Simplified by Electric Cardiometry in Children
Recruiting now
Conditions studied: Circulatory Failure, Shock State, Fluid Therapy
In brief
In this study of diagnostic accuracy, the investigators aim to validate a faster, simpler, and noninvasive test of fluid-responsiveness in critically ill children. This test is based on an assessment of the hemodynamic effects of a standardized abdominal compression, using electrical cardiometry. This would help physicians to identify more easily which patient could benefit from a volume expansion, thus avoiding a potentially useless or even dangerous fluid expansion that could lead to fluid overload. To this end, the diagnostic accuracy of electrical cardiometry-based stroke volume (SV) variation induced by a standardized abdominal compression to predict fluid responsiveness (define as a 15% increase in echocardiographically measured SV after volume expansion) will be measured.
Key facts
- Study ID
- NCT07522580
- Run by
- University Hospital, Bordeaux
- People needed
- 42
- Starts
- 2025-07-22
- Expected to finish
- 2027-08-19
- Last updated by the study team
- 2026-04-13
Who can join
Age: any, up to 8. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age less than or equal to 8 years old
- Hospitalization in a pediatric intensive care unit
- Prescription by the attending physician of a fluid expansion of 10ml/kg
- Use of a non-invasive cardiac output monitoring device (electrical cardiometry) as part of routine care
You may not qualify if…
- Patient less than 37 weeks' corrected gestational age
- Hemodynamic instability making the delay necessary for any test dangerous
- Supine position contraindicated or deleterious
- Impairment of echocardiographic acoustic window or restless patient making ultrasonography impossible
- Opposition to participate expressed by the patient or by a parent or legal guardian
- Intra-abdominal hypertension, painful abdominal palpation or abdominal surgery in the last 15 days
Where it is running
- Hôpital Cardiologique Haut Lévêque - CHU de Bordeaux — Pessac, France, France (enrolling)
- Hôpital Marie Lannelongue — Le Plessis-Robinson, France, France
- Hôpital Arnaud de Villeneuve - CHU de Montpellier — Montpellier, France, France
- Hôpital mère-enfant - CHU de Nantes — Nantes, France, France
Full record on ClinicalTrials.gov
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