Integrated Rehabilitation in HDU for Post-Intensive Care SyndromeLiberation in Patients With PICS

Starting soon · Not applicable

Conditions studied: Post-Intensive Care Syndrome (PICS), Critical Illness Recovery, Mechanical Ventilation

In brief

Post-intensive care syndrome (PICS) is characterized by persistent physical, cognitive, and psychological impairments among survivors of critical illness. Although advances in intensive care medicine have reduced mortality, a large proportion of ICU survivors experience long-term functional impairments after discharge. High-dependency units (HDUs) serve as transitional care settings between intensive care units and general wards. Many critically ill survivors who cannot directly return home are transferred to HDU for continued treatment and rehabilitation. However, evidence regarding systematic multidisciplinary rehabilitation interventions in HDU settings remains limited. This prospective single-center interventional study aims to evaluate the effects of an integrated multidisciplinary rehabilitation model implemented in the HDU on physical, cognitive, and psychological outcomes among patients with post-intensive care syndrome. All enrolled patients will receive standardized integrated medical, nursing, and rehabilitation interventions. Multidimensional functional assessments will be conducted at baseline, during hospitalization, and before discharge from the HDU.

Key facts

Study ID

NCT07521540

Run by

Hongying Jiang, MD

People needed

250

Starts

2026-04-01

Expected to finish

2027-12-31

Last updated by the study team

2026-04-13

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥18 years
• Diagnosed with post-intensive care syndrome
• Transferred from ICU to HDU
• Available paired admission and discharge data

You may not qualify if…

• Death within 24 hours after HDU admission
• Missing primary outcome data

Where it is running

• Beijing Rehabilitation Hospital Affiliated to Capital Medical University — Beijing, Shijingshan, China

Full record on ClinicalTrials.gov

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