Predictive Value of Gastrointestinal Blood Flow for Enteral Nutrition Intolerance in Critically Ill Patients

Recruiting now

Conditions studied: Critical Illness, Enteral Nutrition Intolerance, Enteral Nutrition Feeding, Prediction Models, Machine Learning

In brief

This study aims to explore the correlation between gastrointestinal blood flow and the incidence of enteral nutrition intolerance (ENI) and its symptoms in critically ill patients, construct and compare predictive models including blood flow parameters, and evaluate their incremental predictive value.

Key facts

Study ID

NCT07521111

Run by

Ruijin Hospital

People needed

500

Starts

2026-01-25

Expected to finish

2027-06-30

Last updated by the study team

2026-04-09

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age > 18 years old.
• Expected duration of enteral nutrition support > 7 days.
• Patients or their legal representatives sign the informed consent form.

You may not qualify if…

• History of major gastrointestinal surgery such as subtotal gastrectomy and gastrointestinal anastomosis.
• Contraindications to abdominal point-of-care ultrasound (POCUS) examination (e.g., recent large-area abdominal burns, dressings blocking movement, open abdomen).
• Presence of severe gastrointestinal diseases such as gastroparesis, intestinal obstruction, digestive tract perforation, and gastrointestinal bleeding upon admission.
• Presence of severe peripheral vascular disease or valvular heart disease.
• Pregnant or lactating women.

Where it is running

• Ruijin Hospital, Shanghai Jiao Tong University School of Medicine — Shanghai, China (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.