Evaluating The Use of CGF Made Gel in Mandibular Extraction Sites of Lower Impacted 3rd Molars.
Starting soon · Not applicable
Conditions studied: Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy, Postoperative Pain Management in Oral Surgery, Concentrated Growth Factor for Extraction Socket Healing
In brief
The goal of this clinical trial is to learn if Concentrated Growth Factor (CGF) Gel help improve bone healing and reduce pain after the surgical removal of impacted lower third molars. The study aims to answer the following: Does packing CGF Gel into the extraction site improve bone density? Does the use of CGF Gel reduce postoperative pain for the patient? Researchers will evaluate the healing outcomes of patients receiving this treatment in a prospective case series study. Because this is a case series, all participants will receive the CGF Gel intervention rather than being compared to a placebo group. Participants in this study will: Undergo a blood draw to create the autologous CGF Gel from their own growth factors. Undergo the surgical extraction of an impacted lower third molar under local anesthesia. Have a CGF Gel placed in the extraction socket immediately following the tooth removal. Report their pain levels using a numeric scale on Day 1, Day 3, and Day 7 after surgery. Return for a follow-up CBCT scan three months after the procedure to evaluate bone density changes.
Key facts
- Study ID
- NCT07520097
- Run by
- Cairo University
- People needed
- 10
- Starts
- 2026-05-01
- Expected to finish
- 2026-12-30
- Last updated by the study team
- 2026-04-09
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Patients aged 18 years or older .
- Both male and female patients .
- Patients requiring odontectomy of an impacted lower third molar .
You may not qualify if…
- Patients who are pre-surgically symptomatic .
- Use of medications that affect bleeding time or bone remodeling .
- Patients with a history of radiotherapy or chemotherapy .
- Patients who are pregnant or lactating .
- Patients using oral contraceptives .
- Patients with acute or chronic infections .
- Patients with any kind of pathology confirmed radiographically .
Full record on ClinicalTrials.gov
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