The Effect of Dormicum-Ketamine Versus Dexmedetomidine on Emergence Delirium During Deep Sedation in Paediatric Burn Patients

Recruiting now · Phase 2

Conditions studied: Emergence Delirium in Pediatric Anesthesia

In brief

The aim of this study is to compare the effects of dormicum-ketamine versus dexmedetomidine on postoperative emergence delirium in pediatric patients undergoing deep sedation for burn-related procedures

Key facts

Study ID

NCT07519863

Run by

Ain Shams University

People needed

60

Starts

2025-11-20

Expected to finish

2026-12-01

Last updated by the study team

2026-04-09

Who can join

Age: 3 and older, up to 16. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age from 3 to 16 years
• Both sexes
• Patients classified as American Society of Anesthesiologists (ASA) Physical -Status I-II
• Patients scheduled for elective burn-related procedures (e.g., burn dressing changes or minor interventions)

You may not qualify if…

• Refusal or inability to provide written informed consent from parent or legal guardian
• Known allergy or hypersensitivity to any of the study medications (midazolam, ketamine, or dexmedetomidine)
• Presence of hepatic dysfunction
• Presence of renal dysfunction
• Presence of immunological or hematological disorders
• History of epilepsy, developmental delay (mental retardation), or neurological deficits
• Patients receiving or requiring high doses of inotropes and/or vasopressors intraoperatively or postoperatively
• Preoperative hemodynamic instability, defined as uncontrolled hypertension, hypotension, or bradycardia

Where it is running

• Ain Shams University — Cairo, Egypt (enrolling)

Full record on ClinicalTrials.gov

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