The Impact of Perianal Disease on Patient's Sex Life

Recruiting now

Conditions studied: Perianal Crohn Disease, Perianal Fistula, Fistula in Ano, Perianal Abscess, Pilonidal Cyst/Fistula, Anal Fissure and Fistula

In brief

Perianal diseases, such as perianal abcesses, anal fistulae and perianal Crohn's disease, are often associated with significant physical symptoms, including pain and chronic drainage. However, the impact of these conditions on a patient's personal life, intimacy, and body image-often referred to as "hidden morbidity"-is frequently overlooked in clinical practice. The purpose of this prospective observational study is to evaluate the psychosexual burden in patients suffering from chronic perianal disease. Using validated tools (IIEF-5 for men, FSFI-6 for women) and a specialized Supplemental Patient-Reported Outcome Measure (PROM), researchers will investigate how the presence of surgical devices (such as setons), disease etiology, and clinical symptoms affect sexual function and self-esteem. The study also aims to identify gaps in physician-patient communication regarding sexual health. By quantifying these impacts, the study seeks to promote a more holistic, patient-centered approach to the surgical management of perianal conditions.

Key facts

Study ID

NCT07519850

Run by

AHEPA University Hospital

People needed

60

Starts

2026-03-31

Expected to finish

2026-06-20

Last updated by the study team

2026-04-09

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of chronic perianal disease (fistula-in-ano, pCD, pilonidal).
• Age >18 years.
• Ability to understand and complete the Greek versions of the IIEF-5/FSFI-6 and the study PROM.
• Signed informed consent.

You may not qualify if…

• Active malignancy (colorectal or anal cancer).
• Major pelvic surgery in the last 3 months (unrelated to perianal disease).
• Cognitive impairment preventing survey completion.

Where it is running

• AHEPA University General Hospital — Thessaloniki, Thessaloniki, Greece (enrolling)

Full record on ClinicalTrials.gov

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