Serum Myostatin and Irisin Levels in Postmenopausal Women: Association With Bone Mineral Density and Muscle Strength

Starting soon

Conditions studied: Osteoporosis, Osteopenia

In brief

This study aims to evaluate the relationship between serum myostatin and irisin levels and bone mineral density and muscle strength in postmenopausal women. Participants will be grouped according to bone mineral density as normal, osteopenic, or osteoporotic. Serum myostatin and irisin levels will be measured, and muscle strength will be assessed using handgrip strength and the five times sit-to-stand test. The associations between biochemical and functional parameters will be analyzed.

Key facts

Study ID

NCT07519551

Run by

Kanuni Sultan Suleyman Training and Research Hospital

People needed

60

Starts

2026-04-03

Expected to finish

2026-05-30

Last updated by the study team

2026-04-09

Who can join

Age: 50 and older, up to 65. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Postmenopausal women aged between 50 and 65 years Availability of bone mineral density measurement by dual-energy X-ray absorptiometry (DEXA) Willingness to participate in the study

You may not qualify if…

• Presence of malignancy Chronic kidney disease Chronic liver disease Neuromuscular disorders Recent major surgery or trauma Use of medications affecting bone or muscle metabolism

Full record on ClinicalTrials.gov

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