Association Between Early Recurrence and Long-Term Recurrence After Pulsed Field Ablation for Atrial Fibrillation: Prospective Real-World Evidence From China
Recruiting now
Conditions studied: Atrial Fibrillation (AF)
In brief
The goal of this observational study is to analyze the predictive value of early recurrence within different time windows for late recurrence, ultimately providing evidence-based support for defining the blanking period after pulsed field ablation and stratifying recurrence risk, with the goal of transforming clinical management strategies following pulsed field ablation. The main questions it aims to answer are: 1. Employ big data analysis methods to develop a risk stratification tool for atrial fibrillation; 2. Identify high-risk prognostic indicators for atrial fibrillation and establish early assessment models for short-term and long-term prognosis. Participants will undergo pulsed field ablation for the treatment of atrial fibrillation and will receive structured follow-ups at 1, 3, 6, and 12 months post-ablation. At each follow-up, a 24-hour Holter monitor will be performed to systematically assess the recurrence of atrial arrhythmias and the atrial arrhythmia burden.
Key facts
- Study ID
- NCT07518966
- Run by
- West China Hospital
- People needed
- 1200
- Starts
- 2025-06-16
- Expected to finish
- 2027-06-30
- Last updated by the study team
- 2026-04-15
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients aged ≥18 years
- Study participants diagnosed with atrial fibrillation (AF) and scheduled to undergo pulsed field ablation
- Study participants undergoing their first ablation procedure for AF
You may not qualify if…
- Study participants with any known contraindications to the pulsed field ablation system, anticoagulation therapy, use of contrast agents, or atrial fibrillation ablation
- Those who have previously undergone atrial fibrillation ablation, or have severe mitral stenosis, valve replacement, or various cardiac surgeries.
Where it is running
- West China Hospital, Sichuan University — Chengdu, Sichuan, China (enrolling)
Full record on ClinicalTrials.gov
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