Theophylline, Versus Sumatriptan and Gabapentin in The Treatment of Post-Dural Puncture Headache
Recruiting now · Not applicable
Conditions studied: Theophylline, Sumatriptan, Gabapentin, Post-Dural Puncture Headache
In brief
The aim of this study is to compare the safety and efficacy of theophylline, sumatriptan, and gabapentin in the treatment of post-dural puncture headache.
Key facts
- Study ID
- NCT07515456
- Run by
- Tanta University
- People needed
- 75
- Starts
- 2024-12-01
- Expected to finish
- 2026-11-01
- Last updated by the study team
- 2026-04-07
Who can join
Age: 21 and older, up to 50. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age from 21 to 50 years.
- Both sexes.
- American Society of Anesthesiologists (ASA) physical status ≤ II.
- Patient's selection for this study will be based on clinical diagnosis suggesting post-dural puncture headache (PDPH) based on the International Headache Society criteria.
- Patients with numeric rating scale (NRS) of ≥ 5.
You may not qualify if…
- Pregnant women.
- History of; chronic headache, cluster headache, migraine, convulsions, cerebrovascular accident, and previous neurological diseases.
- Signs of meningismus.
- Dysrhythmia.
- Hypertension.
- Ischemic heart disease.
- Hyperthyroidism.
- Peripheral vascular disease (ischemic colitis).
- Liver or renal impairment.
- Use of selective serotonin reuptake inhibitors.
- Use of ergotamine derivatives in the past 24 hours.
- Use of monoamine oxidase inhibitors in the last 2 weeks.
- Use of any kind of opiates.
- Allergy to the study medications and any contraindication of oral intake.
Where it is running
- Tanta University — Tanta, El-Gharbia, Egypt (enrolling)
Full record on ClinicalTrials.gov
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