A Study to Assess Adverse Events, Tolerability, and Pharmacokinetics of Subcutaneous Injections of ABBV-295 in Healthy Adult Japanese Participants With Overweight or Obesity.
Recruiting now · Phase 1 · Has a placebo group
Conditions studied: Healthy Volunteer
In brief
The purpose of this study is to assess the adverse events, tolerability, and Pharmacokinetics (PK) of subcutaneous injections of ABBV-295 in healthy adult Japanese participants with overweight or obesity.
Key facts
- Study ID
- NCT07514260
- Run by
- AbbVie
- People needed
- 24
- Starts
- 2026-03-31
- Expected to finish
- 2027-01-01
- Last updated by the study team
- 2026-04-15
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Japanese participant must be first-or second-generation Japanese of full Japanese parentage.
- First-generation participants will have been born in Japan to two parents and four grandparents also born in Japan of full Japanese descent.
- Second-generation participants born outside of Japan must have two parents and four grandparents born in Japan of full Japanese descent.
- BMI is ≥ 23.0 to ≤ 35.0 kg/m2 after rounding to the tenths decimal at Screening. BMI is calculated as weight in kg divided by the square of height measured in meters.
You may not qualify if…
- Participant has a self-reported change in body weight ≥ 5% within 3 months prior to Screening.
- HbA1c ≥ 6.5% and/or serum glucose ≥ 126 mg/dL at Screening.
- Participant has taken a medication for the purpose of treating obesity (e.g. Glucagon-like peptide-1, (GLP-1) agonists, Glucagon-like peptide-1/glucose-dependent insulinotropic polypeptide (GLP-1/GIP) agonists, bupropion-naltrexone, orlistat, metformin, phentermine-topiramate, amphetamine based stimulants, methylphenidate) or has been enrolled in an obesity trial within 180 days prior to study treatment administration.
Where it is running
- CenExel ACT- Anaheim Clinical Trials /ID# 280879 — Anaheim, California, United States (enrolling)
Full record on ClinicalTrials.gov
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