MRI Assessment of Velopharyngeal Anatomy After Modified Furlow-Buccinator Flap in Late Primary Palate Repair

Starting soon · Not applicable

Conditions studied: Cleft Palate, Cleft Palate, Unilateral, Complete, Cleft Lip, Cleft Alveolus and Cleft Palate, Cleft Palate Repair

In brief

The goal of this case series study is to learn if magnetic resonance imaging (MRI) can show how well the palate and throat muscles work at rest and during speech after late cleft palate repair. The surgery uses a technique in which the muscle from the cheek is used to close the gap and repair the cleft and therefore improve speech. The study will answer the question of whether this technique will provide better closure and improved speech in the participants who have not received early treatment. The participants will have the surgery and then have MRI scans 6 months after surgery while resting and speaking specific sounds. Complete speech assessments will also be done 6 months after surgery.

Key facts

Study ID

NCT07514091

Run by

Cairo University

People needed

10

Starts

2026-06-01

Expected to finish

2027-06-01

Last updated by the study team

2026-04-07

Who can join

Age: 5 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Non-syndromic cleft palate (La Veau I-IV)
• No prior palatal surgery
• Consent for MRI and follow-up

You may not qualify if…

• Syndromic clefts or associated craniofacial anomalies.
• Systemic co-morbidities
• Previous palatal surgery.
• Contraindications to MRI.

Where it is running

• Cairo University — Cairo, Egypt

Full record on ClinicalTrials.gov

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