Evaluating Intermittent Fasting In Individuals At High Risk ForPancreatic Cancer Undergoing Screening

Starting soon · Not applicable

Conditions studied: Evaluating, Intermittent Fasting, Pancreatic Cancer

In brief

To learn whether an eating pattern called intermittent fasting (IF) is tolerable and feasible for individuals at high risk of pancreatic cancer and whether IF is associated with changes in biological markers, including metabolic, inflammatory, microbiome, and imaging-related markers.

Key facts

Study ID

NCT07513116

Run by

M.D. Anderson Cancer Center

People needed

20

Starts

2026-09-17

Expected to finish

2029-03-30

Last updated by the study team

2026-04-14

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Participants ≥ 18 years old. Participants under 18 are excluded due to their potential inability to understand and consent independently to the methods required for the study drug use and its potential risks and benefits.
• Participants evaluated and classified as high risk for pancreatic cancer through a High-Risk Pancreatic Cancer Clinic or High-Risk Pancreatic Cyst Clinic, based on established clinical assessment and risk stratification.
• High-risk status may include one or more of the following:
• Hereditary cancer syndromes or known pathogenic germline mutations associated with pancreatic cancer risk
• Family history of pancreatic ductal adenocarcinoma (PDAC)
• Presence of pancreatic cysts or precursor lesions (e.g., IPMN, MCN)
• New-onset diabetes mellitus is considered suspicious for pancreatic cancer
• History of recurrent or chronic pancreatitis
• Eligibility and surveillance risk assessment must be consistent with NCCN (National Comprehensive Cancer Network) Guidelines for Pancreatic Cancer Screening in High- Risk Individuals.
• Participants are able to understand and are willing to sign a written informed consent document.
• Both English-speaking and non-English-speaking participants are eligible for participation
• Participants are willing to make a change in eating time patterns.
• Participants are willing to provide App-tracked fasting time data over the course of the study.

You may not qualify if…

• BMI < 18.5 Kg/m2
• Documented history of symptomatic hypoglycemia
• Pregnant or breastfeeding women
• Cognitively impaired individuals

Where it is running

• MD Anderson Cancer Center — Houston, Texas, United States

Full record on ClinicalTrials.gov

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