A Multicenter Cohort Study of Duchenne and Becker Muscular Dystrophy in Western Chinese Children

Starting soon

Conditions studied: Muscular Dystrophy, Becker, Muscular Dystrophy, Muscular Dystrophy (DMD), Muscular Dystrophy, Duchenne

In brief

This is a prospective, multicenter, longitudinal observational cohort study aimed at understanding the progression of Duchenne Muscular Dystrophy (DMD). The primary objective is to identify and integrate key biomarkers from multiple sources-including motor function assessments, body composition (muscle and fat distribution), clinical laboratory tests, and cardiopulmonary imaging-to delineate comprehensive disease trajectories. By analyzing how these factors change over time in a large cohort, the study seeks to develop a robust model that can identify patterns of disease progression. The ultimate goal is to generate evidence that may aid in forecasting individual patient outcomes and inform the future development of personalized rehabilitation and therapeutic strategies.

Key facts

Study ID

NCT07511920

Run by

West China Second University Hospital

People needed

500

Starts

2026-04-20

Expected to finish

2028-12-31

Last updated by the study team

2026-04-06

Who can join

Age: 1 and older, up to 18. Sex: male. Healthy volunteers: not accepted.

You may qualify if…

• Male participants with genetically confirmed diagnosis of Duchenne Muscular Dystrophy (DMD) or Becker Muscular Dystrophy (BMD)
• Age range: 1 to 18 years old (adjust to your actual age limit)
• Ability to complete study assessments and follow-up visits
• Participants or legal guardians provide written informed consent

You may not qualify if…

• Participants with other neuromuscular disorders that may confound natural history data
• Participation in another interventional clinical trial that could affect disease progression
• Severe comorbidities that prevent completion of study assessments
• Inability to provide informed consent or comply with study procedures

Where it is running

• West China Second University Hospital, Sichuan University — Chengdu, China

Full record on ClinicalTrials.gov

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