Whole-Body Vibration on Balance, Risk of Falling and Quality of Life in Chemotherapy-Induced Peripheral Neuropathy

Starting soon · Not applicable

Conditions studied: Whole Body Vibration, Chemotherapy Induced Peripheral Neuropathy (CIPN), Fall Risk, Fall Prevention, Balance, Quality of Life

In brief

The goal of this clinical trial is to evaluate the efficacy of Whole-body vibration in improving postural control, risk of falling, and quality of life in patients with chemotherapy-induced peripheral neuropathy. The main questions it aims to answer are: Does Whole-body vibration have a significant effect on postural control, risk of falling, and quality of life in patients with chemotherapy-induced peripheral neuropathy? Researchers will compare whole body vibration in addition to traditional exercise to traditional exercise alone to see if Whole-body vibration have a significant effect on postural control, risk of falling, and quality of life in patients with chemotherapy-induced peripheral neuropathy. Participants will: * age between 30-60 years old. * be on chemotherapy for at least one cycle as a treatment of malignant tumors with peripheral neuropathy. * have mild to moderate neuropathy according to mTNS. * be assigned randomly into two equal groups (control group (A) and study group (B)). * Take three sessions per week for eight weeks. * The control group (A) will be treated by selected physical therapy treatment (Strength resistive training, Stretching \& flexibility, Balance training) * The study group (B) will be treated with selected physical therapy treatment in addition to whole-body vibration therapy.

Key facts

Study ID

NCT07508527

Run by

Cairo University

People needed

30

Starts

2026-04-01

Expected to finish

2027-06-01

Last updated by the study team

2026-04-02

Who can join

Age: 30 and older, up to 60. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 30 patients diagnosed with chemotherapy-induced peripheral neuropathy from both genders.
• Their ages will range from 30-60 years old.
• All patients included in this study will be on chemotherapy from at least one cycle as a treatment of malignant tumor.
• The patients will be mild to moderate neuropathy according to mTNS.
• They were medically stable.

You may not qualify if…

• History of other types of neuropathies (i.e., hereditry peripheral neuropathy associated with nutritional agents and paraneoplastic syndrome-related neuropathy…etc).
• Unstable medical condition during chemotherapy
• Patients who are starting new therapy or dose modification during study period
• Morbid obesity body mass index >40%
• History of non-surgically repaired nerve compression injuries such as carpal tunnel, brachial plexopathy, spinal stenosis, and spinal nerve root compression
• History of central nervous system primary or metastatic malignancy.

Full record on ClinicalTrials.gov

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