Immediate Effects of PETTLEP-Based AOMI on Upper Limb Kinematics in Stroke Survivors

Starting soon · Not applicable

Conditions studied: Stroke, Hemiplegia, Hemiplegia and/or Hemiparesis Following Stroke

In brief

The purpose of this study is to investigate the immediate effects of a mental practice technique, called Physical, Environment, Task, Timing, Learning, Emotion, Perspective (PETTLEP)-based Action Observation and Motor Imagery (AOMI), on arm movement in stroke survivors. Stroke often causes difficulty in moving the arm smoothly, leading patients to compensate by using their back or shoulder. In this study, participants will either receive a single session of the AOMI training (watching and mentally practicing a reach-to-grasp movement) or a control relaxation task. The researchers will use a smartphone-based motion capture system (OpenCap) to measure if the mental practice immediately improves the smoothness of the arm movement and reduces compensatory body movements.

Key facts

Study ID

NCT07507552

Run by

Istinye University

People needed

28

Starts

2026-04-01

Expected to finish

2027-03-20

Last updated by the study team

2026-04-09

Who can join

Age: 40 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Female and male adults aged 40 to 80 years with a diagnosis of unilateral ischemic or hemorrhagic stroke.
• Residual voluntary movement activity of the affected upper limb.
• Mild to moderate spasticity (Modified Ashworth Scale ≤ 3).
• Adequate cognitive function to understand and follow verbal instructions (Mini-Mental State Examination ≥ 21).
• Medically stable patients, with no active or uncontrolled systemic illness.
• Ability to sit unsupported for at least 30 minutes and be able to perform brief cognitive-motor exercises.

You may not qualify if…

• Other central nervous system disorders (e.g., Parkinson's disease, multiple sclerosis, traumatic brain injury).
• Musculoskeletal or orthopedic conditions causing restriction of movement in the upper-limb (such as fixed contractures, severe joint deformities, shoulder subluxation).
• Severe sensory deprivation, visual neglect, or inattention that interferes with completion of the task or the ability to engage in motor imagery.
• Uncontrolled seizures, severe cardiovascular instability, or any other contraindication to imagery.

Full record on ClinicalTrials.gov

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