Surgical Glove Compression to Prevent Paclitaxel Neuropathy

Starting soon · Not applicable

Conditions studied: Paclitaxel-Induced Peripheral Neuropathy, Breast Cancer, Surgical Glove

In brief

This study aims to evaluate the effect of surgical glove compression as a prophylactic method to prevent paclitaxel-induced peripheral neuropathy. Participants will be randomly assigned to two groups: one receiving standard care, and the other receiving prophylactic surgical glove compression. The study will compare the development, severity of neuropathy in the hands and fingers, and its impact on quality of life.

Key facts

Study ID

NCT07504770

Run by

Necmettin Erbakan University

People needed

84

Starts

2026-03-26

Expected to finish

2027-03-26

Last updated by the study team

2026-04-17

Who can join

Age: 18 and older, up to 80. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Patients aged between 18 and 80 years
• Diagnosed with Stage II-III breast cancer
• No distant metastasis
• Planned to receive adjuvant or neoadjuvant paclitaxel for at least 12 weeks
• Willing and able to provide informed consent
• Eastern Cooperative Oncology Group (ECOG) performance status ≤ 2 Karnofsky ≥ 60%)

You may not qualify if…

• Recurrent breast cancer
• Prior treatment associated with neuropathy (e.g., taxanes, platinum-based chemotherapy, anti-tubulin or proteasome inhibitors)

Where it is running

• Necmettin Erbakan University, Faculty of Health Sciences — Konya, Meram, Turkey (Türkiye)

Full record on ClinicalTrials.gov

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