Influence of Training Session Duration on Improvements in Physiological Resilience to Exercise

Recruiting now · Not applicable

Conditions studied: Endurance Exercise, Healthy Volunteers

In brief

During prolonged endurance exercise, certain physiological variables deteriorate depending on the duration of the exercise. Physiological resilience has therefore been defined as the ability to resist these changes and appears to be an important performance factor in endurance sports. For example, most studies in this field have investigated changes in cycling power output associated with the first ventilatory threshold (VT1), a marker of an individual's endurance capacity, after prolonged endurance exercise. To date, only two studies have examined the effects of training on resilience. The first compared the effectiveness of two training programs, one with low-intensity sessions and the other with high-intensity sessions, with no difference between the conditions. The second study showed that incorporating strength training into a running training program was more effective at improving resilience than running alone. However, the influence of training session duration on resilience remains unknown. Only one observational study has shown that in a group of runners of similar ability, those who were used to doing long sessions had better resilience than those who only did short sessions.

Key facts

Study ID

NCT07504003

Run by

Centre Hospitalier Universitaire de Saint Etienne

People needed

40

Starts

2026-04-08

Expected to finish

2029-02-28

Last updated by the study team

2026-04-14

Who can join

Age: 18 and older, up to 45. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Subjects who engage in rigorous cardiovascular activity (e.g., endurance sports, team sports, combat sports, etc.) for a maximum of two hours per week
• Ability to understand, speak, read, and write French
• Affiliated with or beneficiaries of a social security system
• Having freely given their written consent after being informed of the purpose, procedure, and potential risks involved

You may not qualify if…

• Subjects with chronic joint conditions (e.g., recurrent sprains, patellar or ligament problems).
• Subjects with one or more heart conditions, including ischemic, valvular, arrhythmic, hypertensive, congenital, or hypertrophic heart disease.
• Participants under guardianship or conservatorship.
• Subjects with chronic or central neurological conditions.
• Subjects who report having taken products prohibited by the World Anti-Doping Agency.
• Pregnant or breastfeeding women.
• Subjects who are unable to understand the purpose and conditions of the study and unable to give their consent.
• Persons deprived of their liberty by judicial or administrative decision, persons receiving psychiatric care under Articles L. 3212-1 and L. 3213-1 who are not covered by the provisions of Article L. 1121-8, and persons admitted to a health or social care facility for purposes other than research.

Where it is running

• Service de physiologie clinique et de l'exercice — Saint-Etienne, France (enrolling)

Full record on ClinicalTrials.gov

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