Effectiveness of a Multimodal Outpatient Supervised Physical Activity Program to Improve Tolerance and Efficacy of Chemotherapy in Adults With Breast, Lung and Colon Cancer

Starting soon · Not applicable

Conditions studied: Breast Cancer, Lung Cancer (Non-Small Cell), Colorectal Cancer, Physical Activity, Neoadjuvant Chemotherapy Tolerance, Strength and Endurance

In brief

This clinical study evaluates whether a supervised, multimodal therapeutic exercise program started before chemotherapy and continued during treatment can improve treatment outcomes in patients aged 35 to 65 years with breast, lung, or colon cancer. The study hypothesis is that participation in this exercise program improves tolerance to chemotherapy, allowing patients to receive more than 85% of the planned relative dose intensity. In addition, the program is expected to enhance treatment effectiveness by increasing the rate of complete radiological response. The main objective of the study is to assess the effectiveness of a supervised, multimodal therapeutic exercise program performed before and during chemotherapy in improving both treatment tolerance and treatment efficacy in patients with breast, lung, and colon cancer.

Key facts

Study ID

NCT07502963

Run by

University of Vic - Central University of Catalonia

People needed

70

Starts

2026-04-01

Expected to finish

2027-10-01

Last updated by the study team

2026-03-31

Who can join

Age: 35 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Women and men aged 35 to 65 years
• Diagnosed with stage II, III, or IV breast, lung, or colon cancer
• Scheduled to start neoadjuvant chemotherapy
• Able and willing to provide written informed consent

You may not qualify if…

• Musculoskeletal or neurological disorders that prevent proper execution of the exercises
• Uncontrolled infections or symptoms
• Comorbidities such as chronic obstructive pulmonary disease (COPD), respiratory failure, or recent cardiovascular events within the past 6 months
• Body mass index (BMI) over 35
• Pregnant women
• Difficulty understanding the purpose and procedures of the study

Where it is running

• Consorci Hospitalari de Vic — Vic, Barcelona, Spain
• Facultat de Ciències de la Salut i del Benestar de la Universitat de Vic (UVIC-UCC) Universitat de Vic- Universitat Central de Catalunya — Vic, Barcelona, Spain
• Hospital Universitari de la Santa Creu — Vic, Barcelona, Spain

Full record on ClinicalTrials.gov

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