BIG Chicago: A Trial of Basic Income Guarantee for Young People Living With HIV

Recruiting now · Not applicable

Conditions studied: HIV, Financial Stress

In brief

The goal of this clinical trial is to compare two interventions - Basic Income Guarantee (BIG) + Treatment as Usual and Treatment as Usual among individuals living with HIV who have experienced financial hardships. The main question it aims to answer is: Compared with the Treatment as Usual group, will participants in the BIG + Treatment as Usual group be more likely to improve care engagement and viral suppression? Participants on the study will be: * Randomly assigned (like the flip of a coin) to participate in either BIG + Treatment as Usual or Treatment as Usual. Participants will have an equal chance of being placed in either group. * Complete 9 surveys over a 36 month period. * Complete a release of information so electronic medical record data can be accessed for the 18 months prior to treatment engagement and for 36 months from program enrollment. * Participants in the Treatment as Usual group will not receive any intervention. * HIV viral load testing will be confirmed at 3 timepoints (baseline, 12 months, and 18 months). * Participants in the BIG + Treatment as Usual group will receive $500 monthly income for 18 months. * Participants in the BIG + Treatment as Usual group will complete 3 social network surveys to assess how receiving BIG impacts their social networks. * A subset of participants in the BIG + Treatment as Usual group (30 participants) will complete 5 individual interviews over the course of receiving BIG and the 18 months after.

Key facts

Study ID

NCT07502365

Run by

University of Chicago

People needed

304

Starts

2026-07-29

Expected to finish

2030-07-01

Last updated by the study team

2026-08-06

Who can join

Age: 18 and older, up to 35. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Living with HIV for 24 months or longer;
• Ages 18-35;
• English-speaking;
• One or both of the following:
• Experienced a gap in HIV provider care of 6 or greater months during the prior 12-month period;
• Had an unsuppressed viral load at any point within the prior 12-month period (unsuppressed meaning a viral load of 200 copies/mL or higher);
• Household income at or below 250% of the Federal Poverty Level; and
• Experiencing financial distress, as based on a financial well-being score of 1-4 (high financial distress).

You may not qualify if…

• Unwilling/unable to provide informed consent
• Unable to confirm HIV status
• Unable to conduct the study in English

Where it is running

• University of Chicago — Chicago, Illinois, United States (enrolling)

Full record on ClinicalTrials.gov

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