Investigating the Impact of Cold Atmospheric Plasma Treatment on Wound Healing at Cannulation Sites in Patients Following Extracorporeal Life Support

Recruiting now · Not applicable

Conditions studied: ExtraCorporeal Life Support (ECLS), Wound Infection, Surgical Site Infection, Delayed Wound Healing, Biofilm-Associated Infection

In brief

This study aims to evaluate a new wound treatment called cold atmospheric plasma (CAP) for patients receiving extracorporeal life support (ECLS). Patients on extracorporeal life support (ECLS) often develop wounds at the sites where tubes are inserted, and these wounds can be difficult to heal and prone to infection. cold atmospheric plasma (CAP) is a gentle, non-heat treatment that can kill bacteria, reduce inflammation, and promote wound healing. In this study, patients will be randomly assigned to receive either standard wound care alone or standard care plus cold atmospheric plasma (CAP) treatment. Researchers will compare both groups to see whether cold atmospheric plasma (CAP) can reduce infection, improve healing speed, and decrease the need for additional procedures. The study will also monitor safety to ensure the treatment is well tolerated. The goal is to find a more effective and safe way to improve wound healing in critically ill patients.

Key facts

Study ID

NCT07501897

Run by

National Taiwan University Hospital

People needed

65

Starts

2026-03-12

Expected to finish

2026-12-31

Last updated by the study team

2026-03-30

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥ 18 years
• Receiving extracorporeal life support (ECLS)
• Presence of cannulation site wound requiring wound care

You may not qualify if…

• Pre-existing severe dermatological conditions at the cannulation site
• Severe coagulopathy precluding local intervention
• Concurrent receipt of other experimental wound treatments
• Life expectancy < 48 hours

Where it is running

• National Taiwan University Hospital — Taipei, Taiwan (enrolling)

Full record on ClinicalTrials.gov

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