Sympathetic Ablation for Ventricular Arrhythmias

Starting soon · Not applicable

Conditions studied: Ventricular Tachycardia (VT)

In brief

Enrolled patients will undergo an acute procedure in which a catheter is inserted near the heart to ablate a sympathetic nerve, reducing signals that trigger ventricular arrhythmias.

Key facts

Study ID

NCT07501819

Run by

SymKardia

People needed

10

Starts

2026-04-01

Expected to finish

2027-09-01

Last updated by the study team

2026-03-30

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18 or older at the time of informed consent
• Willing and capable of providing written informed consent
• Implanted ICD or CRT-D
• Recurrent VT leading to ICD therapy (ATP or shock)
• Indicated for catheter ablation of VT per international guidelines
• No prior instrumentation or resection of the stellate ganglia, or surgical procedure that may have disturbed the stellate ganglia

You may not qualify if…

• Contraindication to percutaneous femoral arterial access
• Heparin-induced thrombotic thrombocytopenia
• Prior surgical sympathectomy
• ECMO therapy in the past 30 days
• Contraindicated for advanced heart failure therapies (LVAD or heart transplantation)
• A most recently documented LVEF <20% in the past 30 days
• Receiving inotropic drug therapy
• Women of childbearing potential who are pregnant or breastfeeding. Women of childbearing potential must have a negative pregnancy test at enrollment
• A life expectancy of less than 12 months according to physician judgment
• Involvement in any concurrent clinical study with an investigational therapy

Full record on ClinicalTrials.gov

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