Effect of Early Time-Restricted Eating on Appetite, Appetite-Regulatory Hormones and Energy Intake

Starting soon · Not applicable

Conditions studied: Healthy Adult Male

In brief

This randomised crossover study's primary aim is to investigate the effect of short-term fasting (eTRE) on subjective appetite and appetite-regulatory hormones (i.e., leptin, adiponectin, total glucagon-like peptide-1 (GLP-1), gastric inhibitory polypeptide (GIP), total peptide YY (PYY), acylated ghrelin and Insulin). In addition, to examine if the one-day early time-restricted eating influences energy expenditure and ad libitum energy intake in the periods following the standard meal test. The researchers will compare normal eating with early Time-Restricted Eating (eTRE) in healthy men.

Key facts

Study ID

NCT07500792

Run by

University of Glasgow

People needed

12

Starts

2026-05-01

Expected to finish

2027-11-30

Last updated by the study team

2026-04-16

Who can join

Age: 18 and older, up to 65. Sex: male. Healthy volunteers: accepted.

You may qualify if…

• Males aged 18 years or older.
• BMI between 18.5 and 24.9 kg/m²
• Have stable body mass for at least three months (within ±2 kg).

You may not qualify if…

• Females
• People who are younger than 18 or older than 65 years old.
• Following a special diet (e.g. weight loss, vegetarian or vegan, etc.).
• Have food allergies related to the study.
• Smoking.
• Taking any medications.
• Suffering from metabolic health issues, e.g., history of diabetes, cardiovascular disease, or eating disorders.

Where it is running

• New Lister Building at Glasgow Royal Infirmary Glasgow, United Kingdom G31 2ER — Glasgow, United Kingdom

Full record on ClinicalTrials.gov

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