Intrathecal Ziconotide in Chemotherapy Induced Peripheral Neuropathy
Starting soon
Conditions studied: Chemotherapy Induced Peripheral Neuropathy (CIPN)
In brief
The purpose of this observational, data collection, research is to evaluate if ziconotide, a commercially approved medication given by a FDA cleared intrathecal pump, for chronic pain is effective in the treatment of chemotherapy-induced peripheral neuropathy (CIPN) a common and often long-lasting side effect of cancer treatment.
Key facts
- Study ID
- NCT07499882
- Run by
- Christian Hospital Northeast Northwest
- People needed
- 24
- Starts
- 2026-05-02
- Expected to finish
- 2028-05-01
- Last updated by the study team
- 2026-03-30
Who can join
Age: 18 and older, up to 100. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Adult patients, ages 18-100, with chemotherapy-induced peripheral neuropathy as a primary source of pain
- The patient is already scheduled to be treated with TDD using ziconotide (no reported allergies to ziconotide or drug-drug interactions expected)
- Patient will have, or is scheduled to have, Medtronic Synchromed Intrathecal Pump implanted by Dr. Beuer (outside of the research)
- Patients already taking nonopioid analgesics will be allowed to continue their prescribed medication regimen.
- Patients currently taking opioid analgesics must undergo a washout period of 2 weeks (prior to device implant) before participating in this study. Those unable to adhere to this washout period will be excluded
You may not qualify if…
- Patients with other forms of neuropathy (diabetic, idiopathic) will be excluded
- Patients with a spinal cord stimulator will be excluded
- Patients with contraindications to intrathecal ziconotide will be excluded
- Patients who cannot sign the consent, participate in research activities, or those who require a legally authorized representative (LAR) will be excluded
- Patients who are pregnant and/or nursing or planning to become pregnant are excluded
- Also excluded are those inaccessible for follow-up, participation is excluded by local law, or a patient is currently enrolled or plans to enroll in a concurrent drug/device study
Where it is running
- Christian Hospital — St Louis, Missouri, United States
Full record on ClinicalTrials.gov
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