Effect of Local Application of 1% Metformin Gel on Implant Stability and Peri-implant Bone Density: A Randomized Controlled Study
Recruiting now · Not applicable
Conditions studied: Dental Implant, Stability
In brief
This randomized controlled clinical study aims to evaluate the effect of local application of 1% metformin gel on implant stability and peri-implant bone density. Patients requiring dental implants will be randomly allocated into two groups: a control group and a test group receiving metformin gel. Implant stability will be assessed using resonance frequency analysis, and bone density will be evaluated using CBCT imaging. The outcomes will be compared over a follow-up period to determine the effectiveness of metformin in enhancing osseointegration
Key facts
- Study ID
- NCT07497568
- Run by
- University of Baghdad
- People needed
- 34
- Starts
- 2025-11-01
- Expected to finish
- 2027-06-01
- Last updated by the study team
- 2026-03-27
Who can join
Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- 1) Patients age at least 18 years old. 2) Patient with partial edentulous teeth bounded areas that need dental implant for teeth replacement.
- Adequate bone volume for implant placement (at least 5 mm width - 10 mm height).
- Ability to tolerate conventional surgical and restorative procedures. 5) Patients who are willing to comply the study and give their consent.
You may not qualify if…
- 1) Active infection or inflammation in the implant zone. 2) Presence of any uncontrolled systemic diseases. 3) Patient with history of chemotherapy or radiotherapy. 4) Patient had undergone bone grafting and soft tissue procedures prior to implant surgery.
- Patient had undergone tooth extraction at the implant site less than 6 months prior to implant surgery.
Where it is running
- University of Baghdad -Collage of Dentistry — Baghdad, Baghdad Governorate, Iraq (enrolling)
Full record on ClinicalTrials.gov
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