Anti-Inflammatory Effects of Pecan Nut Oil Supplementation in Adults With Overweight: A Randomized Controlled Parallel-Group Clinical Trial
Recruiting now · Not applicable
Conditions studied: Overweight (BMI > 25)
In brief
The goal of this clinical trial is to evaluate whether daily supplementation with cold-pressed pecan nut oil can reduce inflammation in adults with overweight. The main questions it aims to answer are: Does pecan nut oil supplementation reduce inflammatory biomarkers, including C-reactive protein (CRP), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α)? Does pecan nut oil supplementation improve biochemical parameters such as fasting blood glucose and lipid profile? Researchers will compare an experimental group receiving pecan nut oil to a control group with no intervention to determine its effect on inflammation and metabolic parameters. Participants will: Consume 30 g/day of cold-pressed pecan nut oil under fasting conditions for 8 weeks (experimental group) Maintain their usual diet and physical activity throughout the study Attend two evaluation visits (baseline and Day 60) for blood sample collection and anthropometric measurements Provide dietary information using a 24-hour dietary recall
Key facts
- Study ID
- NCT07497555
- Run by
- Universidad Autonoma de Nuevo Leon
- People needed
- 50
- Starts
- 2025-10-15
- Expected to finish
- 2026-07-30
- Last updated by the study team
- 2026-03-27
Who can join
Age: 18 and older, up to 55. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Adults aged 18 to 65 years
- Body mass index (BMI) ≥25 and <30 kg/m² (overweight)
- Willingness to participate and provide written informed consent
- Ability to comply with study procedures and attend scheduled visits
- Stable dietary habits and physical activity levels during the study period
You may not qualify if…
- Diagnosis of chronic diseases such as diabetes mellitus, cardiovascular disease, liver disease, renal disease, or autoimmune disorders
- Use of anti-inflammatory medications, lipid-lowering drugs, or dietary supplements within the last 3 months
- Smoking or excessive alcohol consumption
- Pregnancy or lactation
- Known allergy or intolerance to nuts or nut-derived products
- Participation in another clinical trial within the last 3 months
- Any condition that, in the investigator's opinion, may interfere with study participation or outcomes
Where it is running
- Facultad de Salud Pública y Nutrición, Universidad Autónoma de Nuevo León — Monterrey, Nuevo León, Mexico (enrolling)
Full record on ClinicalTrials.gov
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