Comparison of Diagnostic Methods in Patients Operated for Suspected Appendicitis
Recruiting now
Conditions studied: Acute Appendicitis
In brief
Acute appendicitis is one of the most common surgical emergencies, but diagnostic uncertainty may still lead to unnecessary appendectomy in some patients. This prospective observational study aims to evaluate the diagnostic performance of computed tomography (CT) reporting and the Appendicitis Inflammatory Response (AIR) score in adult patients undergoing appendectomy for suspected acute appendicitis. The primary objective is to determine the negative appendectomy rate based on final histopathology. Secondary objectives are to assess the agreement between AIR score, CT findings, intraoperative severity grading, and pathology results, and to explore diagnostic performance across patient subgroups. No study-specific intervention beyond routine clinical care will be performed.
Key facts
- Study ID
- NCT07496723
- Run by
- Sanliurfa Education and Research Hospital
- People needed
- 200
- Starts
- 2026-03-18
- Expected to finish
- 2027-01-31
- Last updated by the study team
- 2026-04-01
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age 18 years or older
- Presentation to the emergency department with suspected acute appendicitis
- Underwent computed tomography after clinical evaluation
- Computed tomography report compatible with acute appendicitis
- Underwent appendectomy for presumed acute appendicitis
- Provided informed consent
You may not qualify if…
- Age younger than 18 years
- Pregnancy
- Planned additional surgical intervention in the same session for a reason other than appendicitis
- Intraoperative finding of a non-appendiceal pathology requiring a different surgical procedure
- Refusal to participate in the study
Where it is running
- Sanliurfa Education and Research Hospital — Sanliurfa, Şanlıurfa, Turkey (Türkiye) (enrolling)
Full record on ClinicalTrials.gov
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