Virtual Reality Cognitive Intervention for Critically Ill Delirium Survivors (VR-Cog)
Recruiting now · Not applicable
Conditions studied: Intensive Care Unit Delirium, Intensive Care Acquired Cognitive Impairment, Post Intensive Care Unit Syndrome, Virtual Reality Cognitive Training
In brief
The purpose of this study is to measure the feasibility, acceptability of virtual reality (VR) brain games and estimate their effect on memory, attention, and mood for ICU survivors. The VR program will be used at home through a headset and hand controls.
Key facts
- Study ID
- NCT07496255
- Run by
- Indiana University
- People needed
- 100
- Starts
- 2026-03-19
- Expected to finish
- 2027-07-15
- Last updated by the study team
- 2026-04-17
Who can join
Age: 50 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Adults aged 50 years or older
- English speaking
- Admitted to the intensive care unit (ICU) with acute respiratory failure/invasive mechanical ventilation
- Screening positive for delirium (using Richmond Agitation Sedation Scale and Confusion Assessment Method for the ICU)
You may not qualify if…
- Acute neurologic injury such as stroke, traumatic brain injury, brain mass, intracranial hemorrhage, seizures, or central nervous system infection
- Chronic cognitive or physical function deficit preventing participation in study interventions or assessments (determined by chart diagnoses and direct participant interview)
- Chronic cognitive impairment (including mild cognitive impairment or dementia) identified by chart diagnosis, prescription of anti-dementia medications, or Informant Questionnaire on Cognitive Decline in the Elderly Score (IQCODE) >3.3 obtained from family caregiver
- Severe, uncorrected vision or hearing impairment preventing participation in intervention or outcomes assessments
- Admitted with acute alcohol or drug intoxication or withdrawal
- Severe, uncontrolled psychiatric disorder (bipolar disorder or schizophrenia)
- History of severe vertigo, motion-induced sickness, headaches, light sensitivity, seizures, or prior intolerance of virtual reality (VR)
- Receiving comfort care measures or not expected to survive the hospitalization
- Prisoners or patients unable to provide consent
- Not expected to be discharged home from the hospital, or living more than 50 miles from the nearest recruitment site, or homeless
Where it is running
- IU Health Methodist Hospital — Indianapolis, Indiana, United States (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.