Effects of Post-Isometric Relaxation and Myofascial Release on Low Back Pain With Lower Cross Syndrome

Starting soon · Not applicable

Conditions studied: Low Back Pain, Mechanical, Lower Cross Syndrome, Hamstring Muscle Tightness

In brief

This randomized controlled trial aims to evaluate the combined effects of post-isometric relaxation and myofascial release on pain, flexibility, and functional disability in individuals with low back pain associated with lower cross syndrome. Eligible participants aged 18 to 45 years will be randomly allocated into two parallel intervention groups. One group will receive post-isometric relaxation combined with myofascial release, while the comparison group will receive conventional stretching combined with Therapeutic modalities. Outcomes will be assessed at baseline and after completion of the intervention period. The results of this study are expected to contribute to evidence-based physiotherapy management of low back pain associated with postural imbalance.

Key facts

Study ID: NCT07496099
Run by: University of Karachi
People needed: 60
Starts: 2026-03-25
Expected to finish: 2026-10-20
Last updated by the study team: 2026-03-27

Who can join

Age: 18 and older, up to 45. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Participants aged 18-45 years old
having low back pain persisting for at least 4 weeks
with clinical diagnosis of LCS, and hamstring tightness (AKE >15°)

You may not qualify if…

Participants with the history of spinal surgery active neurological conditions
systemic disease affecting connective tissue (Rheumatoid arthritis, Systemic lupus erythematosus)
recent lower limb or spinal injury (within 6 months)
pregnancy or inability to lie prone for treatment.

Where it is running

Department of Physiotherapy, University of Karachi — Karachi, Sindh, Pakistan

Full record on ClinicalTrials.gov

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