An AI-Based Erythema Measurement System for Psoriasis Lesions
Starting soon
Conditions studied: Psoriasis
In brief
Psoriasis is a common chronic inflammatory skin disease. Disease severity is commonly assessed using the Psoriasis Area and Severity Index (PASI), in which erythema is graded subjectively on a 0-4 scale. This visual assessment is prone to significant inter- and intra-rater variability. Although objective tools such as colorimeters provide accurate erythema measurement, their high cost limits routine clinical use. Smartphone imaging combined with artificial intelligence (AI) offers a practical alternative for objective assessment. However, variability in lighting conditions can affect image consistency. Incorporating a color calibration card enables accurate color normalization. This study aims to develop and validate an AI-based system for measuring erythema in psoriatic lesions using smartphone images with a color card, compared against a standard colorimeter to assess validity and reliability.
Key facts
- Study ID
- NCT07494396
- Run by
- Khon Kaen University
- People needed
- 50
- Starts
- 2026-11-01
- Expected to finish
- 2027-04-20
- Last updated by the study team
- 2026-08-05
Who can join
Age: 18 and older, up to 100. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Adults aged ≥18 years
- Diagnosed with psoriasis by a dermatologist
- Presence of at least five clearly photographable lesions
- Willing and able to take photographs using a smartphone with both a standard color calibration card and a study-specific color card at home weekly, and submit images via Line or email
- Willing to have clinical photographs taken at baseline and at a follow-up visit
- Provides written informed consent to participate in the study
You may not qualify if…
- Presence of skin infection or other lesions that may interfere with color assessment (e.g., tattoos)
- Use of self-tanning products or substances that alter skin color
- Inability to perform photography or comply with study procedures
Where it is running
- Khon Kaen University — Khon Kaen, Changwat Khon Kaen, Thailand
Full record on ClinicalTrials.gov
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