Effects of Changes in Driving Pressure on Intraoperative Pulmonary Dynamic Compliance and PaO₂/FiO₂ Ratio in Laparoscopic Sleeve Gastrectomy

Starting soon · Not applicable

Conditions studied: Dynamic Lung Compliance

In brief

The goal of this prospective intervention study is to determine whether individualized positive end expiratory pressure (PEEP) titration targeting the minimum Driving pressure (ΔP) during LGS operation improves intraoperative pulmonary dynamic compliance (Cdyn), oxygenation, post operative pulmonary complication (PPCS) Participants will be assigned to two group (incremental - fixed )peep group Researchers will compare the two group to see if peep titration improve lung compliance, lung mechanics intraopertive and PPCS

Key facts

Study ID

NCT07494240

Run by

Beni-Suef University

People needed

46

Starts

2026-04-15

Expected to finish

2027-10-15

Last updated by the study team

2026-03-27

Who can join

Age: 20 and older, up to 60. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• BMI 35 -40kg·m-²
• ASA II-III
• Elective primary laparoscopic sleeve gastrectomy

You may not qualify if…

• Patient refusing consent
• ASA IV patients.
• Sever pulmonary disease
• Sever obstructive sleep apnea (OSA)
• Hepatic or cardic or renal imparment

Where it is running

• Beni-Suef University Hospital — Banī Suwayf, Beni Suweif Governorate, Egypt

Full record on ClinicalTrials.gov

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