Dose Dependent Steroid Injections

Starting soon · Phase 4

Conditions studied: Lumbar Radiculopathy, Sciatica, Back Pain With Radiation

In brief

This study aims to evaluate the efficacy of interlaminar steroid injections at treating pain in lumbar radiculopathy at varying doses, to evaluate the efficacy of interlaminar steroid injections at improving quality of life and function in lumbar radiculopathy at varying doses, and to evaluate difference in efficacy between triamcinolone and dexamethasone interlaminar steroid injections at treating pain in lumbar radiculopathy at varying doses, with the overarching hypotheses that there is no difference in reported pain reduction, quality of life, or function among patients receiving low, moderate, or high doses, and no difference in reported pain reduction between triamcinolone and dexamethasone.

Key facts

Study ID

NCT07494136

Run by

University of Miami

People needed

150

Starts

2026-05-01

Expected to finish

2027-05-01

Last updated by the study team

2026-03-27

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults able to consent
• Lumbar radiculopathy with MRI-confirmed pathology
• No history of back surgery
• Use of interlaminar approach lumbar spine injections
• No use of oral pain medication other than Tylenol or Acetaminophen during the 6 weeks after injection

You may not qualify if…

• Adults unable to consent
• Individuals who are not yet adults (infants, children, teenagers)
• Pregnant women
• History of back surgery
• Use of oral pain meds other than Tylenol or Acetaminophen during the 6 weeks after injection

Where it is running

• University of Miami — Miami, Florida, United States

Full record on ClinicalTrials.gov

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