Comparison of Gait Metrics in Patients With Stroke, Traumatic Brain Injury, and Multiple Sclerosis

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Conditions studied: Stroke, Traumatic Brain Injury, Multiple Sclerosis

In brief

People with neurological conditions often have difficulty walking, including problems such as foot drop. Functional electrical stimulation (FES) is a treatment that uses electrical signals to activate muscles and support walking. The L300 device is designed to help lift the foot during each step. This study will evaluate how using the L300 affects walking performance. Researchers will measure walking speed, step length, and walking symmetry using objective gait assessment tools. The study will also explore whether people with different neurological conditions respond differently to FES. The goal of this research is to improve understanding of how FES influences walking and to support more personalized rehabilitation approaches.

Key facts

Study ID

NCT07492602

Run by

Casa Colina Hospital and Centers for Healthcare

People needed

90

Starts

2026-04-01

Expected to finish

2027-02-01

Last updated by the study team

2026-03-27

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults aged 18-80 years.
• Diagnosis of stroke, traumatic brain injury, or multiple sclerosis confirmed by medical records.
• Presence of foot drop or impaired ankle dorsiflexion during gait.
• Ability to ambulate at least 10 meters with or without assistive devices.
• Cognitive ability to follow simple instructions and provide informed consent.

You may not qualify if…

• Severe lower limb contractures or orthopedic conditions that limit gait.
• Implanted electrical devices (e.g., pacemaker) contraindicating FES use.
• Uncontrolled medical conditions (e.g., severe cardiac disease).
• Pregnancy.
• Skin integrity issues preventing electrode placement.
• Participation in other interventional gait studies within the past 3 months.

Where it is running

• Casa Colina Hospital and Centers for Healthcare — Pomona, California, United States

Full record on ClinicalTrials.gov

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